China 3415-08-5 L-Tyr-NCA Onye nrụpụta na ụlọ ọrụ |Jiayinglai

3415-08-5 L-Tyr-NCA

Nkọwa dị mkpirikpi:

Ọdịdị	kristal na-acha ọcha ruo na-acha ọcha ma ọ bụ ntụ ntụ kristal
MF	C10H9NO4
MW	207.18
Ịdị ọcha	98+

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Nkọwa ngwaahịa

Ọnọdụ njem&ụkpụrụ mbupu akwadoro:
site n'ikuku, site n'oké osimiri ma ọ bụ site na awara awara

Ọnọdụ nchekwa:
ikuku ikuku, Chekwaa na friza, n'okpuru -20 Celsius

Ọnụ ahịa kacha nta:
Mkparịta ụka

Asambodo:
COA, HPLC, GC, HNMR, Assay, Ọdịnaya Mmiri (KF), TLC dị

Ụdị okwu

Tyrosine, NCA;

N-Carboxy-L-tyrosine anhydride;

(4S) -4- [(4-Hydroxyphenyl) methyl] -2,5-oxazolidinedione;

L-Tyrosine N-carboxyanhydride;

(2,5-Oxazolidinedione,4-[(4-hydroxyphenyl) Methyl] -, (4S) -;

N-Carbonyl-L-Tyrosine Anhydride

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha ebu ntụ ntụ.Ha nwekwara ike igbochi anwụ na mmiri ime ihe ọjọọ.

mpụta mbukota

Katọn ahụ siri ike nwere ike ichekwa ngwaahịa gị ka ọ ghara ịdaba na mmiri.

Ngwa

3415-08-5 L-Tyr-NCA bụ otu n'ime etiti Glatiramer Acetate.

Glatiramer acetate bụ peptide a kwadebere nke ọma nke mejupụtara amino acid anọ: glutamic acid, alanine, tyrosine, na lysine.Ngwa ya bụ isi dabere na ọgwụgwọ Multiple Sclerosis (MS), ọrịa na-adịghị ala ala, nke na-ewe iwe, na-arịa ọrịa demyelinating na-emetụta sistemu ụjọ nke etiti.Site na usoro nke "nkwụsị nkwụsị," Glatiramer Acetate na-arụ ọrụ immunomodulatory na mgbochi mkpali na MS, na-amụba ọkwa nke ụbụrụ neurotrophic nke ụbụrụ na-enweta (BDNF), na-ebelata mbufụt na-akpata demyelination, na-akwalite uto nke axon na myelin sheaths.

N'ụwa niile, Glatiramer Acetate enwetala ngwa zuru ebe niile.Dịka ọmụmaatụ, na United States, a na-ere ya n'okpuru akara aha Copaxone ma ndị nchịkwa nri na ọgwụ ọjọọ (FDA) kwadoro ya maka ọgwụgwọ Multiple Sclerosis.Na mba ndị dị n'Ebe Ọdịda Anyanwụ nwere nnukwu MS, a matala ịdị irè ya na nnabata ya nke ọma.

Na China, na June 28, 2023, "Glatiramer Acetate Injection" nwetara nkwado site na National Medical Products Administration (NMPA) maka ọgwụgwọ nke ndị ọrịa toro eto nwere nlọghachi azụ Multiple Sclerosis (MS), gụnyere ọrịa dịpụrụ adịpụ nke ụlọ ọgwụ, nlọghachi-na-akwụsị. MS, na MS na-aga n'ihu nke abụọ na-arụ ọrụ.

ngwaahịa ndị metụtara ya

L-Gly-NCA	L-Ala-NCA	D-Ala-NCA	L-Val-NCA
D-Leu-NCA	DL-leu-NCA	L-Phe-NCA	D-Tyr-NCA
L-Tyr(bzl)-NCA	L-Glu(Obzl) -NCA	D-Asp(OBzl) -NCA	L-Lys(tfa) -NCA
L-Lys (Cbz) -NCA	D-Lys (Cbz) -NCA	Sar-NCA

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