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Boc-His (Boc) - Aib-OH

Boc-His (Boc) - Aib-OH

Nkọwa dị mkpirikpi:

Ọdịdị Na-acha ọcha na-acha ọcha ntụ ntụ
MF
MW
Ịdị ọcha 98+


Nkọwa ngwaahịa

Ọnọdụ njem
Nwere ike ịdị na okpomọkụ nkịtị

Kwado usoro mbupu
Site ikuku Site n'ala Site n'oké osimiri

Ọnọdụ nchekwa:
Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, okpomọkụ ụlọ

ndụ shelf
Ihe dị ka afọ 2

Ọnụ ego kacha nta:
1kg (mkparịta ụka)

Asambodo:COA, ebe mgbaze, SpecificRotation [α]D20                      

Anyị ga-eziga data ọ bụla ịchọrọ.Ị nwere ike ịhụ data n'ihu dị ka ntụaka.

Maka ngwaahịa ahaziri ahazi, anyị na-eziga data kachasị ọhụrụ mgbe ha pụtachara.

D-Lys(tfa) -NCA (2)

Ntụpọ

Boc-His (Boc) - Aib-OH

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha eme ihe maka ịkwakọba ntụ ntụ.Ọ dabere na ihe ndị ahịa chọrọ.Ya mere, gwa anyị ihe ị na-achọ tupu ịkwakọ ngwaahịa ma ọ bụrụ na ị nwere arịrịọ pụrụ iche.

Nkwakọ ngwaahịa dị n'ime 2
Nkwakọ ngwaahịa dị n'ime 1
Nkwakọ ngwaahịa dị n'ime 3

mpụta mbukota

1kg ruo 25kg Mbukota mpụta siri ike.Ọ na-esikwa ike ịkpụ na imebi.Ọ nwere ike ichekwa ngwaahịa gị nke ọma.

Mkpokọta mpụta 3
Mkpokọta mpụta 2
Nkwakọ ngwaahịa dị n'èzí 1

Ngwa

Peptide Synthesis na Mgbanwe: Boc-His (Boc) -Aib-OH nwere ike ije ozi dị ka ihe mgbochi ụlọ n'ime agbụ peptide, na-enye aka iwu nke peptides nwere usoro na ọrụ kpọmkwem site na ijikọta na amino acid ndị ọzọ ma ọ bụ akụkụ peptide.Ihe peptides ndị a na-emepụta nke ọma nwere ọtụtụ ngwa na nchọpụta ọgwụ, nyocha biochemical na mpaghara ndị ọzọ metụtara ya.
Nyere ọnụnọ nke histidine (His) na α-aminoisobutyric acid (Aib), ihe pụrụ iche nke amino asịd ndị a na-enye Boc-His (Boc) -Aib-OH nwere ọrụ dị mkpa na ụfọdụ usoro peptide.Ha nwere ike ịkwalite nkwụsi ike na ọrụ ndu nke peptides.
Nnyocha na iwu gbasara ihe omume ndu:Boc-His(Boc) -Aib-OH nwere ihe omume ndu, na-eme ka ọ bụrụ ngwa bara uru maka ọmụmụ ihe omume ndu.Ndị na-eme nchọpụta nwere ike iwebata ya n'ime usoro ihe ndị dị ndụ iji hụ mmetụta ọ na-enwe na usoro cellular, si otú ahụ na-enweta nghọta miri emi na usoro physiological na pathological.
Site n'ịgbanwe ìgwè imidazole nke histidine na usoro pụrụ iche nke α-aminoisobutyric acid, Boc-His (Boc) -Aib-OH nwere ike imetụta mmekọrịta ya na ndị na-anabata ya ma ọ bụ ihe ndị ọzọ na-emepụta ihe, na-achịkwa mmeghachi omume ndu kpọmkwem ma ọ bụ ụzọ ntụgharị mgbaàmà.
Nhazi na mmepe ọgwụ:Boc-His(Boc) -Aib-OH na-ejide uru ngwa nwere ike na mpaghara nchọpụta ọgwụ.Mgbanwe ihe owuwu ma ọ bụ njikarịcha nwere ike iduga na ogige nwere mmemme ọgwụ pụrụ iche, na-eje ozi dị ka ọgwụ ndị na-eme ntuli aka maka nyocha na mmepe ọzọ.
N'ịtụle ihe nwere ike ime metal ion chelating Njirimara nke imidazole otu histidine na biocompatibility nke α-aminoisobutyric acid, Boc-His (Boc) -Aib-OH nwere ike emebe maka ọhụrụ ọgwụ mmepe na-ezubere iche ọrịa kpọmkwem ma ọ bụ ndu.
Nyocha biochemical na Biophysical: Boc-His (Boc) -Aib-OH nwere ike ịrụ ọrụ dị ka ihe atụ maka ịmụ usoro mmekọrịta dị n'etiti peptides na biomolecules dị ka protein na DNA, yana mpịakọta peptide na nkwụsi ike n'ime usoro ndu.

Site na nyocha n'ime mmekọrịta ya na biomolecules dị iche iche, enwere ike nweta nghọta miri emi nke njirimara biochemical na ọrụ nke peptides.

ngwaahịa ndị metụtara ya

L-Ya-OH HD-Ya-OH H-His(trt)-OH Boc-L-His(Boc) -OH.Dcha
Boc-His (Boc) - OH Boc-D-His (Boc) -OH Fmoc-D-His (Fmoc) -OH FMOC-His (BOC) -OH
Boc-L-His (Trt) -Aib-OH

Gịnị mere Họrọ Anyị

1. Banyere MOQ: Anyị nwere ike ịhazigharị ya dịka ihe ị chọrọ.
2. Banyere ihe atụ: Ihe nlele ahụ chọrọ ego nlele, nke nwere ike ibu ibu iji nakọta ma ọ bụ ị nwere ike ịkwụ anyị ụgwọ tupu oge eruo.
3. Ụlọ ihe omumu ihe, enwere ike ịhazi ya dị ka ọnụ ọgụgụ nke ụdị.
4. Anyị na-enye ọrụ kacha mma.Otu ndị ahịa nwere ahụmahụ na-arụ ọrụ maka gị.
5. Banyere mgbanwe: Biko email ma ọ bụ kpaara m nkata na gị mma.


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