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40216-83-9 H-Hyp-Ome·HCl

40216-83-9 H-Hyp-Ome·HCl

Nkọwa dị mkpirikpi:

Ọdịdị Ọcha ntụ ntụ
MF C6H12ClNO3
MW 181.62
Ịdị ọcha 98+


Nkọwa ngwaahịa

Ọnọdụ njem
Nwere ike ịdị na okpomọkụ nkịtị

Kwado usoro mbupu
Site ikuku Site n'ala Site n'oké osimiri

Ọnọdụ nchekwa:
Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, okpomọkụ ụlọ

Ndụ nchekwa
Ihe dị ka afọ 2

Ọnụ ego kacha nta:
1kg (mkparịta ụka)

Asambodo:COA, ebe mgbaze, SpecificRotation [α]D20                      

Anyị ga-eziga data ọ bụla ịchọrọ.Ị nwere ike ịhụ data tupu dị ka ntụaka.

Maka ngwaahịa ahaziri ahazi, anyị na-eziga data kachasị ọhụrụ mgbe ha pụtachara.

D-Lys(tfa) -NCA (2)

Ụdị okwu

H-HYP-OMEHCL;
HL-HYP-OMEHCL;
HYDROXYPROLINE-OMEHCL;
(2S, 4R) -trans-4-hydroxy-L-prolinemethylesterhydrochloride;
4-hydroxy-2-pyrrolidinecarboxylicacidmethylesterhydrochloride;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCLORIDE;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDESALT;
L-4-TRANS-HYDROXYPROLINEMETHYLESTERHYDROCLORIDE

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha eme ihe maka ịkwakọba ntụ ntụ.Ọ dabere na ihe ndị ahịa chọrọ.Ya mere, gwa anyị ihe ị na-achọ tupu ịkwakọ ngwaahịa ma ọ bụrụ na ị nwere arịrịọ pụrụ iche.

Nkwakọ ngwaahịa dị n'ime 2
Nkwakọ ngwaahịa dị n'ime 1
Nkwakọ ngwaahịa dị n'ime 3

mpụta mbukota

1kg ruo 25kg Mbukota mpụta siri ike.Ọ na-esikwa ike ịkpụ na imebi.Ọ nwere ike ichekwa ngwaahịa gị nke ọma.

Mkpokọta mpụta 3
Mkpokọta mpụta 2
Nkwakọ ngwaahịa dị n'èzí 1

Ngwa

Na-eji: H-Hyp-OMe·HCl na-eje ozi dị ka ADC na-adịghị ekewapụ (antibody-drug conjugate) njikọ maka njikọ nke ADCs.ADCs, nke mejupụtara ọgwụ mgbochi na cytotoxin jikọtara site na njikọ ADC, na-eme ka nnyefe nke cytotoxins gaa na sel, si otú a na-agwọ ọrịa ụfọdụ.Na mgbakwunye, H-Hyp-OMe·HCl bụ njikọ PROTAC (protein deradaration targeting chimera) dabere na ụdọ alkyl, ejiri na njikọ nke PROTAC.PROTACs, nke nwere njikọ abụọ dị iche iche jikọtara ya na onye na-ejikọta ya, na-eji sistemu ubiquitin-proteasome cellular iji weda protein dị iche iche.

Njirimara: H-Hyp-OMe·HCl bụ ntụ ntụ amorphous na-acha ọcha ma ọ bụ na-acha odo odo nke na-agbaze na ihe mgbaze dị ka mmiri, methanol, na ethanol.Ọ na-egosipụta nkwụsi ike dị mma na biocompatibility, na-ejigide ọrụ ya na nkwụsi ike n'okpuru ọnọdụ physiological.

N'ozuzu, H-Hyp-OMe·HCl na-arụ ọrụ dị mkpa na njikọ nke ADCs na PROTAC dị ka ihe dị mkpa reagent biochemical na ngwá ọrụ mmepe ọgwụ.Ọ na-enye ụzọ ọhụrụ na ụzọ maka ọgwụgwọ ọrịa.Ka nyocha na-aga n'ihu na teknụzụ na-etolite, atụmanya ngwa nke H-Hyp-OMe·HCl ga-agbasawanye.

ngwaahịa ndị metụtara ya

L-Hyp-OH HL-Hyp-Ome·HCl
HL-Hyp-Oet.HCl L-Hyp-Obzl.Hcl
Boc-L-Hyp-OH Boc-L-Hyp-Ome
Fmoc-L-Hyp-Ome Boc-L-Hyp-oet
Fmoc-L-Hyp-OH Fmoc-L-Hyp(tbu) -OH
Cbz-L-Hyp-OH Cbz-L-Hyp-OMe

Nke kacha elu

1. Anyị na-enye nhazi ngwaahịa ndị ị chọrọ.
2. Enwere ike ịnye oke mma & ọnụahịa asọmpi.
3. Anyị na-ekwe gị nkwa usoro ọrụ nleba anya zuru oke maka gị.
4. Supplier questionnaire na teknuzu akwụkwọ nwere ike ịnye ma ọ bụrụ na arịrịọ mgbe ezute a ụfọdụ ego.
5. Great mgbe-sales ọrụ ma ọ bụ nkwa : Ọ bụla nke ajụjụ gị ga-edozi ozugbo o kwere omume.
6. Mbupụ ngwaahịa asọmpi na mbupụ ha n'ọtụtụ buru ibu kwa afọ.
7. Ihe nlele efu nyere iji lelee àgwà tupu ịkwụ ụgwọ ọ bụla.


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