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23680-31-1 Tert-butoxycarbonyl-serine (Benzyl) -OH

23680-31-1 Tert-butoxycarbonyl-serine (Benzyl) -OH

Nkọwa dị mkpirikpi:

Ọdịdị kristal na-acha ọcha ruo na-acha ọcha ma ọ bụ ntụ ntụ kristal
MF C15H21NO5
MW 295.33
Ịdị ọcha 98+


Nkọwa ngwaahịa

Ọnọdụ njem
Nwere ike ịdị na okpomọkụ nkịtị

Kwado usoro mbupu
Site ikuku Site n'ala Site n'oké osimiri

Ọnọdụ nchekwa:
Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, okpomọkụ ụlọ

Ndụ nchekwa
Ihe dị ka afọ 2

Ọnụ ego kacha nta:
1kg (mkparịta ụka)

Asambodo:COA, ebe mgbaze, SpecificRotation [α]D20                      

Anyị ga-eziga data ọ bụla ịchọrọ.Ị nwere ike ịhụ data tupu dị ka ntụaka.

Maka ngwaahịa ahaziri ahazi, anyị na-eziga data kachasị ọhụrụ mgbe ha pụtachara.

D-Lys(tfa) -NCA (2)

Ụdị okwu

N-BOC-O-Benzyl-L-ser;
N-Boc-O-benzyl-L-serineBoc-Ser(Bzl)-OH;
(S) -3- (benzyloxy) -2- ((tert-butoxycarbonyl) aMino) propanoicacid;
N-BOC-O-BENZYL-SERINE;
(2S) -3-Benzyloxy-2- (tert-butoxycarbonylamino) propanoicacid;
L-SERINE-NT-BOC,O-BZETHER(15N);
L-SERINE-NT-BOC,O-BZETHER(2-13C)

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha eme ihe maka nkwakọba ntụ ntụ.Ọ dabere na ihe ndị ahịa chọrọ.Ya mere, ọ bụrụ na ị nwere ihe pụrụ iche chọrọ, biko mee ka anyị mara ihe ị chọrọ tupu nkwakọ.

Nkwakọ ngwaahịa dị n'ime 2
Nkwakọ ngwaahịa dị n'ime 1
Nkwakọ ngwaahịa dị n'ime 3

mpụta mbukota

Ngwungwu dị n'èzí siri ike.Ọ dịghịkwa mfe ịkpụ ma mebie ya.Ọ nwere ike ichekwa ngwaahịa gị nke ọma.

Mkpokọta mpụta 3
Mkpokọta mpụta 2
Nkwakọ ngwaahịa dị n'èzí 1

Ngwa

Njikọ Peptide:

Boc-Ser (Bzl) -OH na-eje ozi dị ka ihe mgbochi ụlọ n'ime usoro siri ike ma ọ bụ ngwọta-phase peptide synthesis.Enwere ike ijikọ ya na amino acid ndị ọzọ ma ọ bụ iberibe peptide iji mepụta peptides ma ọ bụ protein dị ogologo.
Otu benzyl (Bzl) na-echebe ìgwè hydroxyl nke serine, na-enye ohere maka mmeghachi omume nhọrọ na saịtị ndị ọzọ n'ime eriri peptide.
Otu Boc na-echebe otu amino, na-egbochi mmeghachi omume akụkụ na-achọghị n'oge njikọ peptide.
Ọmụmụ biochemical:

Boc-Ser (Bzl) -OH nwere ike iji dị ka reagent na biochemical nnwale na-amụ protein-protein mmekọrịta, enzyme kinetics, na ndị ọzọ molekul bayoloji ngwa.
Site na itinye amino acid a n'ime peptides ma ọ bụ protein, ndị nchọpụta nwere ike nyochaa ọrụ ha na mmekọrịta ha na ụmụ irighiri ihe ndị ọzọ.
Nchọpụta ọgwụ:

Boc-Ser (Bzl) -OH nwere ike itinye n'ime peptidomimetics ma ọ bụ ọgwụ peptide, nke emebere iji ṅomie ihe omume ndu nke peptides eke.
Ndị a peptidomimetics nwere ike ịnwe ike ọgwụgwọ na mpaghara dịka ọrịa kansa, ọrịa na-efe efe, na nsogbu akwara ozi.
Enwere ike wepu otu benzyl n'oge mmepe ọgwụ iji kpughee otu hydroxyl nke serine n'efu, nke nwere ike ịdị mkpa maka ọrụ ndu nke peptide.
Sayensị ihe onwunwe:

Boc-Ser (Bzl) -OH nwere ike iji mee ihe na njikọ nke biocompatible na biodegradable polymers maka nhazi anụ ahụ, nnyefe ọgwụ, na ngwa ndị ọzọ.
Enwere ike ịmepụta polymers ndị a ka ha wepụta ọgwụ ma ọ bụ mkpụrụ ndụ bioactive n'ụzọ a na-achịkwa, na-eme ka usoro ọgwụgwọ ha dịkwuo mma na ibelata mmetụta.

ngwaahịa ndị metụtara ya

L-Ser H-DL-Ser-OH D-Ser(tBu)-OH
D-Ser (bzl) D-Ser (bzl) .HCl HL-Ser (Bzl) -OH.HCl
HL-Ser(Bzl)-OH HL-Ser (Bzl)-OL.HCl HL-Ser-OBzl.HCl
HL-Ser-OBzl DL-Ser-Obzl.Hcl D-Ser-Obzl.Hcl
HL-Ser(Bzl)-OMe·HCl Boc-L-Ser-OH Boc-L-Ser.H2O
Boc-DL-Ser-OH Boc-D-Ser-OH Boc-L-ser (m) - OH
Boc-L-ser (m).DCHA Boc-DL-Ser (m) -OH Boc-D-ser(m)OH
Boc-L-Ser(tBu) -OH Boc-D-Ser(tBu) -OH Boc-D-Ser (Tbu).DCHA
Boc-L-Ser(Bzl)-OH Boc-DL-Ser (Bzl)-OH Boc-D-Ser(Bzl)-OH
Boc-Ser (Bzl) -ol Boc-D-Ser(Bzl)-OL Boc-L-Ser-OMe
Boc-DL-Ser-Ome Boc-D-Ser-OMe Boc-D-Ser-Oet
Boc-L-Ser-Obzl Boc-D-Ser-Obzl Boc-L-Ser (bzl) -OSu
Fmoc-L-Ser(bzl)-OH Fmoc-D-Ser(bzl)-OH Fmoc-L-Ser-Obzl
Fmoc-N-Me-Ser(bzl) ZL-Ser(Bzl)-OH Cbz-D-Ser(Bzl)-OH
Cbz-L-Ser-Obzl  

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