200937-17-3 Boc-D-Leu-OH•H2O

Biochemistry na nchọpụta ọgwụ:
Dị ka ihe mgbapụta amino acid, Boc-D-Leu-OH·H2O na-arụ ọrụ dị mkpa n'ịmepụta peptides na protein ndị na-arụ ọrụ ndụ.Mgbanwe kemịkalụ nke ogige a nwere ike ibute mmepe nke ọgwụ ọhụrụ ma ọ bụ ndị na-achọ ọgwụ maka ịgwọ ọrịa dị iche iche.Ngwongwo pụrụ iche nke D-leucine nwere ike inyefe peptides ma ọ bụ protein ndị agbakwunyere ihe omume ndụ.
Njikọ Peptide:
Na njikọ peptide siri ike, Boc-D-Leu-OH·H2O bụ isi amino acid monomer.Otu N-terminal Boc na-echebe ya na-enye ohere ka amino acid ligation na deprotection n'okpuru ọnọdụ dị nro, na-eme ka njikọ nke eriri peptide nwere usoro na ọrụ dị iche iche.
Nnyocha ụlọ nyocha:
A na-ejikarị Boc-D-Leu-OH·H2O mee ihe na njikọ peptide na ọmụmụ ihe nhazi protein.Site na ijikọta ya na monomers amino acid ndị ọzọ, enwere ike ịhazi usoro peptide dị iche iche iji nyochaa mmekọrịta protein-protein na protein-ligand, yana ọrụ protein na usoro nhazi.
Peptide Reagents na ihe enyemaka sịntetik:
Boc-D-Leu-OH · H2O nwere ike ije ozi dị ka onye na-ahụ maka nchebe ma ọ bụ onye na-emepụta ihe na-emepụta peptide synthesis, na-eme ka arụmọrụ na ịdị ọcha nke usoro nchịkọta peptide dịkwuo mma.Ọzọkwa, enwere ike iji ya dị ka peptide reagent maka ịde aha peptide, mgbanwe na nchọpụta.
Njikọ nke asymmetric:
N'ihi ọdịdị chiral nke D-leucine, Boc-D-Leu-OH·H2O nwere ngwa nwere ike na njikọ asymmetric.Site na ijikọta ya na ụmụ irighiri ihe ndị ọzọ, peptides na protein nwere ike ịhazi stereoconfigurations iji mụọ mmetụta chirality na ihe omume ndu.