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1799443-50-7 Fmoc-N-Me-D-Tyr(tBu)-OH

1799443-50-7 Fmoc-N-Me-D-Tyr(tBu)-OH

Nkọwa dị mkpirikpi:

Ọdịdị na-acha ọcha ntụ ntụ
MF C29H31NO5
MW 473.56
Ịdị ọcha 98+


Nkọwa ngwaahịa

Ọnọdụ njem
Nwere ike ịdị na okpomọkụ nkịtị

Kwado usoro mbupu
Site ikuku Site n'ala Site n'oké osimiri

Ọnọdụ nchekwa:
Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, okpomọkụ ụlọ

Ndụ nchekwa
Ihe dị ka afọ 2

Ọnụ ego kacha nta:
1kg (mkparịta ụka)

Asambodo:COA, ebe mgbaze, SpecificRotation [α]D20                      

Anyị ga-eziga data ọ bụla ịchọrọ.Ị nwere ike ịhụ data n'ihu dị ka ntụaka.

Maka ngwaahịa ahaziri ahazi, anyị na-eziga data kachasị ọhụrụ mgbe ha pụtachara.

D-Lys(tfa) -NCA (2)

Ntụpọ

(R) -2- (((9H-Fluoren-9-yl) methoxy) carbonyl) (methyl) amino) -3- (4- (tert-butoxy) phenyl) propanoicacid;

(9H-Fluoren-9-yl)MethOxy]CarbonylN-Me-D-Tyr(tBu)-OH;

(2R) -3-[4- (tert-butoxy) phenyl] -2- ({[(9H-fluoren-9-yl) methoxy] carbonyl} (methyl) amino) propanoicacid;

(2R) -2- [9H-fluoren-9-ylmethoxycarbonyl (methyl) amino] -3-[4-[(2-methylpropan-2-yl) oxy] phenyl] propanoicacid;

N-Fmoc-N-methyl-O-tert-butyl-D-tyrosine;

D-Tyrosine, O- (1,1-dimethylethyl) -N-[(9H-fluoren-9-ylmethoxy) carbonyl]-N-methyl-

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha eme ihe maka ịkwakọba ntụ ntụ.Ọ dabere na ihe ndị ahịa chọrọ.Ya mere, gwa anyị ihe ị na-achọ tupu ịkwakọ ngwaahịa ma ọ bụrụ na ị nwere arịrịọ pụrụ iche.

Nkwakọ ngwaahịa dị n'ime 2
Nkwakọ ngwaahịa dị n'ime 1
Nkwakọ ngwaahịa dị n'ime 3

mpụta mbukota

1kg ruo 25kg Mbukota mpụta siri ike.Ọ na-esikwa ike ịkpụ na imebi.Ọ nwere ike ichekwa ngwaahịa gị nke ọma.

Mkpokọta mpụta 3
Mkpokọta mpụta 2
Nkwakọ ngwaahịa dị n'èzí 1

Ngwa

Fmoc-N-Me-D-Tyr (TBu) -OH, nke a makwaara dị ka N-α- (9-fluorenylmethoxycarbonyl) -N-α-methyl-D-tyrosine tert-butyl ester, bụ amino acid echekwabara nke a na-ejikarị eme ihe. na njikọ peptide siri ike.Ngwakọta a na-ejikọta Fmoc nchebe otu maka amino terminus na tert-butyl (TBu) ester na-echebe phenolic hydroxyl otu D-tyrosine.

Otu Fmoc, dị ka e kwuru na mbụ, kwụsiri ike na soluble na organic solvents, na-eme ka ọ dị mma maka njikọ peptide.Enwere ike iwepụ ya ngwa ngwa n'okpuru ọnọdụ alkaline, na-enye ohere maka mgbakọ peptides n'usoro na nkwado siri ike.N'aka nke ọzọ, tert-butyl ester na-echebe ìgwè phenolic hydroxyl nke D-tyrosine, na-eme ka nkwụsi ike ya na ịdị ọcha n'oge usoro nhazi.

Ngwa izizi nke Fmoc-N-Me-D-Tyr (TBu) -OH dị na nkwadebe nke peptides nwere D-tyrosine.Site n'iji usoro amino acid a, ndị nchọpụta nwere ike iwebata D-tyrosine yana ma amino na phenolic hydroxyl dị iche iche echedoro n'ime usoro peptide ha.Nke a na-enye njikwa ziri ezi na nhazi peptide ma na-eme ka iwebata amino acid ndị ọzọ na mgbanwe n'ọnọdụ ụfọdụ n'ime agbụ peptide.

D-Tyrosine bụ amino acid na-abụghị nke okike nke enwere ike itinye n'ime peptides iji mụọ ihe ndị dị ndụ ha ma ọ bụ mepụta peptide analogs nwere ihe emezigharị.Peptides nwere D-tyrosine nwere ike inwe ọrụ ndu dị iche iche ma e jiri ya tụnyere ndị otu L-tyrosine ha, n'ihi ọdịiche stereochemical dị n'etiti amino acid abụọ ahụ.

ngwaahịa ndị metụtara ya

N-Me-Tyr(M) -OH.HCl Boc-N-Me-L-Tyr(tbu)-OH Fmoc-N-Me-L-Tyr(tBu)-OH Cbz-N-Me-Tyr(tbu)-OH
FMOC-N-Me-D-Tyr(m)OH Boc-N-Me-L-Tyr(bzl)-OH Fmoc-N-Me-L-Tyr(bzl)-OH Boc-N-Me-D-Tyr(bzl)-OH

Gịnị mere Họrọ Anyị

1. Banyere MOQ: Anyị nwere ike ịhazigharị ya dịka ihe ị chọrọ.
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