China 166108-71-0 Fmoc-AEEA-OH Onye nrụpụta na ụlọ ọrụ |Jiayinglai

166108-71-0 Fmoc-AEEA-OH

Nkọwa dị mkpirikpi:

Ọdịdị	Na-acha ọcha na-acha ọcha ntụ ntụ
MF	C21H23NO6
MW	385.41
Ịdị ọcha	98+

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Nkọwa ngwaahịa

Ọnọdụ njem
Nwere ike ịdị na okpomọkụ nkịtị

Kwado usoro mbupu
Site ikuku Site n'ala Site n'oké osimiri

Ọnọdụ nchekwa:
Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, okpomọkụ ụlọ

ndụ shelf
Ihe dị ka afọ 2

Ọnụ ego kacha nta:
1kg (mkparịta ụka)

Asambodo:COA, ebe mgbaze, SpecificRotation [α]_D²⁰

Anyị ga-eziga data ọ bụla ịchọrọ.Ị nwere ike ịhụ data n'ihu dị ka ntụaka.

Maka ngwaahịa ahaziri ahazi, anyị na-eziga data kachasị ọhụrụ mgbe ha pụtachara.

Ntụpọ

[2-[2- (Fmoc-amino) ethoxy] ethoxy] acetic acid

Fmoc-8-amino-3,6-dioxaoctanoic acid, Fmoc-AEEA.

Fmoc-PEG2-acetic acid

{2-[2-(Fmoc-amino)ethoxy] ethoxy} acetic acid≥ 99% (HPLC)

Fmoc-NH- (PEG) -COOH (atom 9) Novabiochem

1- (9H-Fluoren-9-yl) -3-oxo-2,7,1-trioxa-4-azadodecan-12-oic acid

9-FLUORENYLETHOXYCARBONYL-8-AMINO-3,6-DIOXAOCTANOIC ACID.

8-(FMOC-AMINO) -3,6-DIOXA-OCTANOIC ACID

8-FLUORENYLMETHOXYCARBONYLAMINO-3,6-DIOXAOCTANOIC Acid.

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha eme ihe maka ịkwakọba ntụ ntụ.Ọ dabere na ihe ndị ahịa chọrọ.Ya mere, gwa anyị ihe ị na-achọ tupu ịkwakọ ngwaahịa ma ọ bụrụ na ị nwere arịrịọ pụrụ iche.

mpụta mbukota

1kg ruo 25kg Mbukota mpụta siri ike.Ọ na-esikwa ike ịkpụ na imebi.Ọ nwere ike ichekwa ngwaahịa gị nke ọma.

Ngwa

166108-71-0 Fmoc-AEEA-OH bụ njikọ ADC nwere ike ihichapụ nke ejiri na njikọ nke conjugates antibody-ọgwụ (ADCs).Fmoc-8-amino-3,6-dioxaoctanoic acid bụkwa ihe njikọ PROTAC dabeere na PEG nke enwere ike iji na njikọ nke PROTAC.

166108-71-0 Fmoc-AEEA-OH nwekwara ike ịbụ otu n'ime semaglutide Intermediates.

Isi mmetụta nke semaglutide bụ ịgwọ ụdị ọrịa shuga 2 site na ibelata ọkwa glucose ọbara.Ọ na-eṅomi insulin-dị ka peptide-1 hormone, nke na-akpali mmepụta insulin na-egbochi mwepụta nke glucagon, si otú ahụ na-ebelata ọkwa glucose ọbara.Semaglutide anaghị etinye aka na ihe ize ndụ nke hypoglycemia na-eme ma e jiri ya tụnyere ọgwụgwọ insulin nke mbụ n'ihi na usoro ya dị mgbagwoju anya na nke ziri ezi.Site n'ịgbanwe nguzozi nke insulin na glucagon, somalutide nwere ike inyere ndị nwere ụdị ọrịa shuga 2 aka ịchịkwa ọkwa shuga ha nke ọma.

Na mgbakwunye na ibelata ọkwa shuga dị n'ọbara, semaglutide nwekwara ike ibelata ibu ahụ.Nke a bụ n'ihi mmetụta na-egbochi agụụ ya.semaglutide na-akpali ọrụ nke satiety center na hypothalamus, nke na-ebelata agụụ.Isi uru nke semaglutide na ọgwụ ndị ọzọ na-ebelata ibu bụ na ọ na-atụfu ibu ma na-eme ka nguzogide insulin na njikwa shuga ọbara dịkwuo elu.Nke a na-eme ka ọ bụrụ nhọrọ ọgwụgwọ a na-achọsi ike maka ndị ọrịa nwere ọrịa shuga nwere oke ibu.

Na mgbakwunye, semaglutide na-eme ka ọrụ pancreatic dịkwuo mma ma na-ebelata nzaghachi mkpali na mkpụrụ ndụ islet pancreatic.Ọ na-echebe mkpụrụ ndụ agwaetiti pụọ na mmebi ọzọ nke ọrịa shuga na-akpata ma na-akwalite mmụgharị mkpụrụ ndụ agwaetiti.Nke a dị mkpa karịsịa maka ndị nwere ọrịa shuga 2dị nke abụọ, n'ihi na oke mmebi nke cell cell nwere ike iduga ọdịda nke agwaetiti.

N'ozuzu, semaglutide bụ ọgwụ dị oke mma yana nchekwa maka ọgwụgwọ ụdị ọrịa shuga 2.Ọ na-enyere ndị ọrịa aka ịchịkwa ọrịa shuga ha nke ọma ma belata nsogbu site n'iweda ọkwa glucose ọbara, ibelata ibu ahụ, meziwanye ọrụ agwaetiti, na ichekwa mkpụrụ ndụ agwaetiti.Ọmụmụ ihe n'ọdịnihu ga-enyochakwu ikike nke somatostatin na ọgwụgwọ ọrịa ndị ọzọ, dị ka NAFLD na oke ibu.

ngwaahịa ndị metụtara ya

Fmoc-AEEA-AEEA-OH

Fmoc-L-Lys(dde)-OH

DDE-Lys(Fmoc) -OH

Gịnị mere Họrọ Anyị

1. Banyere MOQ: Anyị nwere ike ịhazigharị ya dịka ihe ị chọrọ.
2. Banyere ihe atụ: Ihe nlele ahụ chọrọ ego nlele, nke nwere ike ibu ibu iji nakọta ma ọ bụ ị nwere ike ịkwụ anyị ụgwọ tupu oge eruo.
3. Ụlọ ihe omumu ihe, enwere ike ịhazi ya dị ka ọnụ ọgụgụ nke ụdị.
4. Anyị na-enye ọrụ kacha mma.Otu ndị ahịa nwere ahụmahụ na-arụ ọrụ maka gị.
5. Banyere mgbanwe: Biko email ma ọ bụ kpaara m nkata na gị mma.

Nke gara aga: 68858-20-8 Fmoc-L-Val-OH

Osote: 15962-47-7 Ac-L-Ala-NH2

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