ibe_banner

130622-05-8 Tert-butoxycarbonyl-D-glutamic acid (methyl ester) - methyl ester.

130622-05-8 Tert-butoxycarbonyl-D-glutamic acid (methyl ester) - methyl ester.

Nkọwa dị mkpirikpi:

Ọdịdị kristal na-acha ọcha ruo na-acha ọcha ma ọ bụ ntụ ntụ kristal.
MF C12H21NO6
MW 275.3
Ịdị ọcha 98+


Nkọwa ngwaahịa

Ọnọdụ njem&ụkpụrụ mbupu akwadoro:
site n'ikuku, site n'oké osimiri ma ọ bụ site na awara awara

Ọnọdụ nchekwa:
Debe n'ebe gbara ọchịchịrị, mechie ya na nkụ, okpomọkụ ụlọ

Ọnụ ahịa kacha nta:
Mkparịta ụka

Asambodo:
COA, HPLC, GC, HNMR, Assay, Ọdịnaya Mmiri (KF), TLC dị

D-Lys(tfa) -NCA (2)

Ụdị okwu

dimethyl (tert-butoxycarbonyl) -D-glutamate;
(R) -2-tert-Butoxycarbonylamino-pentanedioic acid dimethyl ester;
(Tert-Butoxy) Carbonyl D-Glu(OMe)-Ome (Syrup);
Boc-D-Glu(OMe) -OMe (Syrup);
dimethyl (2R) -2-[(2-methylpropan-2-yl) oxycarbonylamino] pentanedioate;
Alogliptin adịghị ọcha 43;
1,5-dimethyl (2R) -2-{[(tert-butoxy) carbonyl] amino}pentanedioate

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha ebu ntụ ntụ.Ha nwekwara ike igbochi anwụ na mmiri ime ihe ọjọọ.

Nkwakọ ngwaahịa dị n'ime 2
Nkwakọ ngwaahịa dị n'ime 1
Nkwakọ ngwaahịa dị n'ime 3

mpụta mbukota

Katọn ahụ siri ike nwere ike ichekwa ngwaahịa gị ka ọ ghara ịdaba na mmiri.

Mkpokọta mpụta 3
Mkpokọta mpụta 2
Nkwakọ ngwaahịa dị n'èzí 1

Ngwa

Fluoroquinolones nwere ụdị nje antibacterial sara mbara, ọrụ antibacterial siri ike, mmeghachi omume ọjọọ dị ala, ikike anụ ahụ dị mma, bioavailability dị elu nke ọnụ, ogologo oge nchịkwa yana nchịkwa dabara adaba.A na-ejikarị ha agwọ ọrịa na-efe efe dị ka ọrịa iku ume na ọrịa urinary tract.Ọdịdị nke fluoroquinolone ọgwụ nje antibacterial na-egosi ọnụnọ nke fluorine na ọnọdụ nke isii nke quinolone nne na nna nucleus.
Otú ọ dị, n'ime afọ 10 na-adịbeghị anya, n'ihi nrụgide a na-ahọrọ site na ngwa ngwa nke ụdị ọgwụ a, ụdị ọgwụ na-eguzogide ọgwụ na-abawanye, karịsịa n'afọ ndị na-adịbeghị anya, quinolone na-eguzogide Streptococcus pneumoniae nwere cross-resistance, nke na-eguzogide ọgwụ penicillin. ọgwụ nje macrolide na ọgwụ nje quinolone.N'otu oge ahụ, a chọpụtara na ụfọdụ fluoroquinolones nwere ike ime ka QTc ogologo oge nke electrocardiogram, hepatotoxicity na phototoxicity, nke na-ejedebe ngwa ha.
Iji merie mmejọ ndị a dị n'elu nke fluoroquinolones, ọ dị ngwa ịmepụta ogige ọhụrụ nke nwere ezigbo ọrụ antibacterial, nnukwu nje bacteria na dị ka obere mmeghachi omume ọjọọ megide nje bacteria na-eguzogide ọgwụ.Usoro ọgwụ ọhụrụ nke fluoroquinolone-free (NFQ) ọhụrụ mepụtara na nso nso a nwere 8-methoxyl dị iche na ọgwụ nje fluoroquinolone na ha enweghị fluorine na ọnọdụ 6 nke quinolone nne na nna, ma ka nwere ike na vitro antibacterial ọrụ.nemonoxacin bụ nje nje topoisomerase inhibitor nke NFQ ọhụrụ.
E jiri ya tụnyere fluoroquinolones ugbu a n'ahịa, Nenofloxacin na-anọchite anya klaasị ọhụrụ nke ọgwụ arụrụ arụ.nemonocacin (TG-873870), ọgwụ ọhụrụ quinolone nke Procter & Gamble (P&G) mepụtara, gosipụtara ọrụ antibacterial dị ịrịba ama megide ụdị ọrịa dị iche iche metụtara ụlọ ọgwụ, gụnyere Staphylococcus aureus na Streptococcus pneumoniae na-eguzogide ọgwụ.Nsonaazụ nke nnwale na ụmụ oke ndị butere ọrịa gosiri na mmetụta nje bacteria nke ngwaahịa a siri ike karịa ọtụtụ quinolones dị ugbu a.Tụkwasị na nke ahụ, ngwaahịa ahụ nwere ihe ndị dị mma nke pharmacokinetic ma na-anabata ya nke ọma.

ngwaahịa ndị metụtara ya

Fmoc-Gly-glu(otbu)-oh Boc-D-Glu(OBzl)-Oet
HL-Glu-OH Boc-D-Glu(Obzl)-OH
HD-Glu-OH Boc-D-Glu(Ome)-OH
DL-Glu-OH Boc-D-Glu(Ome)-OH.DCHA
DL-Glu-OH.H2O Boc-Glu(OBzl)-Obzl
L-Glu(Obzl) -NCA Boc-L-Glu-OBzl
D-Glu(Obzl) -NCA Boc-D-Glu-Obzl
DL-Glu(Obzl) -NCA Boc-D-Glu-Otbu-OH
L-Glu-Obzl Boc-D-Glu(OMe) -OMe
Tos-Glu-Obzl Boc-D-Glu(Obzl)-Obzl
L-Glu(Ome)-Obzl.TOS Boc-L-Glu(Ome) -Ome
AC-Glu (OtBu) Boc-L-Glu(OMe)-OH
DL-Glu (Ome) Boc-L-Glu(OBzl)-OH
HD-Glu(OMe)-OH Boc-Glu-Otbu
HL-Glu(OMe)-OH Boc-L-Glu(Obzl)-Ome
L-Glu (Obzl) Boc-L-Glu (Oet)
HL-Glu(OtBu) -OH Fmoc-L-Glu-OH
HL-Glu(OEt) - OH Fmoc-D-Glu-OH
L-Glu(Otbu)-Otbu-OH Fmoc-D-Glu(Ome)-OH
HD-Glu(OBzl) -OH Fmoc-L-Glu(OcHx)-OH
D-Glu-OBzl Fmoc-L-Glu(OMe)-OH
HL-Glu(Ome)-Otbu.Hcl Fmoc-L-Glu(OtBu) -OH
D-Glu(Obzl)-Otbu.HCL Fmoc-D-Glu(OBzl)-OH
D-Glu(OtBu)-OtBu•HCl Fmoc-D-Glu(Otbu) -OH
L-Glu (OcHx).hcl Fmoc-L-Glu-OtBu
HL-Glu(OBzl)-OBzl.HCl Fmoc-L-Glu(OBzl) -OH
HL-Glu-OBzl.HCl Fmoc-L-Glu (Cbz-ee)
D-Glu(OBzl)-OBzl.HCl Fmoc-N-Me-L-Glu(Otbu)-OH
DL-Glu(Ome)-Ome.Hcl Fmoc-glu-obzl
HL-Glu(OtBu)-OtBu•HCl Cbz-L-Glu-OH
HL-Glu(OMe)-OMe.HCl Cbz-D-Glu-OH
L-Glu(Obzl)-OME.HCL ZL-Glu-OBzl
HL-Glu(OEt)-OEt·HCl ZD-Glu-OBzl
L-Glu(Obzl)-Otbu.HCl Cbz-L-Glu-Otbu
HD-Glu(OMe)-OMe·HCl Cbz-D-Glu(ome)
N-Pht-Glu Cbz-L-Glu(OBzl)-OH
Boc-L-Glu-OH Cbz-L-Glu(Otbu)
Boc-D-Glu-OH Cbz-L-Glu(Ome)
Boc-Glu(obzl) -NH2 Cbz-D-Glu(OtBu)-OH
Boc-Glu (trt) - OH Cbz-L-Glu(Ome)-OtBu
Boc-L-Glu(OcHx)-OH Cbz-L-Glu-OBzl.DCHA
Boc-L-Glu(OtBu) -OH Cbz-L-Glu(Oet)-OH
Boc-Glu(Osu)-Otbu Boc-Glu-Otbu (Osu)

Nke kacha elu

1. R&D ọrụ dị
2. Onye nrụpụta akwụkwọ ikike ISO, nkwa dị mma
3.A zuru oke nke ọrụ ntinye aka n'oge mmepụta
4.High ọnụ ahịa dị irè
5.Quality akwụkwọ ikike nyere maka arịrịọ ndị ahịa
6.Great after-sales service, ịnọgide na-enwe mmekọrịta chiri anya na ndị ahịa
7.Full akụ iji nyere aka belata ụgwọ mbupu
8.Free sample nyere iji lelee àgwà tupu ịkwụ ụgwọ ọ bụla
9.Payment okwu mkparita uka
Ndị ahịa 10.Assit na-emekọ ihe na China


  • Nke gara aga:
  • Osote:

  • Dee ozi gị ebe a ziga anyị ya