China 1118767-15-9 Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA] -OSu Nrụpụta na Factory |Jiayinglai

1118767-15-9 Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu

Nkọwa dị mkpirikpi:

Ọdịdị	Na-acha ọcha na-acha ọcha ntụ ntụ
MF	C47H82N4O15
MW	943.17
Ịdị ọcha	98+

Zitere anyị email

Nkọwa ngwaahịa

Ọnọdụ njem
Enwere ike ibuga ya na okpomọkụ nkịtị.

Kwado usoro mbupu
site n'ikuku, site n'ala ma ọ bụ site n'oké osimiri

Ọnọdụ nchekwa:
2-8 Celsius C, a ga-edobe ya na mkpuchi, oyi na enweghị anwụ.

ndụ shelf
ihe dị ka afọ 2

Ọnụ ego kacha nta:
1kg (mkparịta ụka)

Asambodo:COA, ebe mgbaze, SpecificRotation [α]_D²⁰Anyị ga-eziga data ọ bụla ịchọrọ.Mana maka ngwaahịa ahaziri ahazi, anyị na-eziga data kachasị ọhụrụ mgbe ha pụtachara.
N'ezie, ị nwere ike ịhụ data n'ihu dị ka ntụaka.

Ntụpọ

Semaglutide etiti

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha eme ihe maka ịkwakọba ntụ ntụ.Ọ dabere na ihe ndị ahịa chọrọ.Ya mere, gwa anyị ihe ị na-achọ tupu ịkwakọ ngwaahịa ma ọ bụrụ na ị nwere arịrịọ pụrụ iche.

mpụta mbukota

1kg ruo 25kg Mbukota mpụta siri ike.Ọ na-esikwa ike ịkpụ na imebi.Ọ nwere ike ichekwa ngwaahịa gị nke ọma.

Ngwa

Nke mbu, a haziri agbụ akụkụ nke semaglutide ma rụọ ọrụ ya, na-arụ ọrụ dị mkpa na ngwa ọgwụ ya.Agbụ n'akụkụ a, jikọtara ya na 26th lysine residue nke agbụ peptide, ọ bụghị naanị na-eme ka nkwụsi ike nke usoro semaglutide dịkwuo mma kamakwa ọ na-eme ka mmekọrịta ya na ụmụ irighiri ihe dị ndụ dị mfe.

Nke abuo, yinye n'akụkụ nwere ụdọ diacid fatty 18-carbon, nke a na-emepụta site na njikọ nke glutamic acid, mkpụrụ ndụ abụọ nke 8-amino-3,6-dioxaoctanoic acid (AEEA), na octadecanedioic acid.Usoro agbụ akụkụ a pụrụ iche na-abawanye mmekọrịta nke semaglutide maka albumin, na-ebelata mkpochapụ akụrụ yana ịgbatị ọkara ndụ ya n'ime ahụ.Ọrụ ogologo oge a na-eme ka mmetụta ọgwụgwọ na ịdịte aka nke ọgwụ ahụ dịkwuo elu.

Ọzọkwa, pegylation nke yinye akụkụ na-eme ka semaglutide solubility na ngagharị iwe, na-ebelata filtration gbasara akụrụ na mmebi proteolytic.Mgbanwe a na-ebelatakwa pyrogenicity nke ọgwụ ahụ ma na-echebe ya pụọ na ọgụ nke usoro ahụ ji alụso ọrịa ọgụ, na-eme ka nnyefe ọgwụ na-ejigide ya na saịtị ahụ.

ngwaahịa ndị metụtara ya

Fmoc-AEEA-OH	Fmoc-AEEA-AEEA-OH	H-Glu-OtBU	Boc-Glu-Otbu(Osu)
Fmoc-L-Ser(tBu) -OH	Fmoc-L-Lys-OH·HCl

Gịnị mere Họrọ Anyị

1. Banyere MOQ: Anyị nwere ike ịhazigharị ya dịka ihe ị chọrọ.
2. Banyere ihe atụ: Ihe nlele ahụ chọrọ ego nlele, nke nwere ike ibu ibu iji nakọta ma ọ bụ ị nwere ike ịkwụ anyị ụgwọ tupu oge eruo.
3. Ụlọ ihe omumu ihe, enwere ike ịhazi ya dị ka ọnụ ọgụgụ nke ụdị.
4. Anyị na-enye ọrụ kacha mma.Otu ndị ahịa nwere ahụmahụ na-arụ ọrụ maka gị.
5. Banyere mgbanwe: Biko email ma ọ bụ kpaara m nkata na gị mma.

Nke gara aga: 1118767-16-0 tBuO-Ste-Glu(AEEA-AEEA-OH) -OtBu

Osote: 1122076-55-4 Fmoc-Glu(OtBu) -Phe-OH

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