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109425-51-6 Fmoc-L-His(Trt) -OH

109425-51-6 Fmoc-L-His(Trt) -OH

Nkọwa dị mkpirikpi:

Ọdịdị Na-acha ọcha na-acha ọcha ntụ ntụ
MF C40H33N3O4
MW 619.71
Ịdị ọcha 98+


Nkọwa ngwaahịa

Ọnọdụ njem
Nwere ike ịdị na okpomọkụ nkịtị

Kwado usoro mbupu
Site ikuku Site n'ala Site n'oké osimiri

Ọnọdụ nchekwa:
Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, okpomọkụ ụlọ

Ndụ nchekwa
Ihe dị ka afọ 2

Ọnụ ego kacha nta:
1kg (mkparịta ụka)

Asambodo:COA, ebe mgbaze, SpecificRotation [α]D20                      

Anyị ga-eziga data ọ bụla ịchọrọ.Ị nwere ike ịhụ data n'ihu dị ka ntụaka.

Maka ngwaahịa ahaziri ahazi, anyị na-eziga data kachasị ọhụrụ mgbe ha pụtachara.

D-Lys(tfa) -NCA (2)

Ntụpọ

N-Fmoc-N'-trityl-L-histidine

FMOC-N-IM-TRITYL-L-HISTIDINE

FMOC-HISTIDINE(1-TRT) -OH

FMOC-HIS (TRITYL) -OH

FMOC-HIS(TRT)

FMOC-HIS(TRT) -OH

FMOC-HIS(T-TRT) -OH

FMOC-HIS(1-TRT) -OH

FMOC-L-HIS (TRITYL)

Nkwakọ ngwaahịa n'ime

A na-ejikarị ha eme ihe maka ịkwakọba ntụ ntụ.Ọ dabere na ihe ndị ahịa chọrọ.Ya mere, gwa anyị ihe ị na-achọ tupu ịkwakọ ngwaahịa ma ọ bụrụ na ị nwere arịrịọ pụrụ iche.

Nkwakọ ngwaahịa dị n'ime 2
Nkwakọ ngwaahịa dị n'ime 1
Nkwakọ ngwaahịa dị n'ime 3

mpụta mbukota

1kg ruo 25kg Mbukota mpụta siri ike.Ọ na-esikwa ike ịkpụ na imebi.Ọ nwere ike ichekwa ngwaahịa gị nke ọma.

Mkpokọta mpụta 3
Mkpokọta mpụta 2
Nkwakọ ngwaahịa dị n'èzí 1

Ngwa

109425-51-6 Fmoc-L-His (Trt) -OH bụ nke L-histidine sitere na ya, nke bụ amino acid dị mkpa mmadụ, ma e jiri ya tụnyere amino acid ndị ọzọ, na mgbakwunye na ụfọdụ mmeghachi omume kemịkalụ L-histidine n'ihi nri ya. N'akụkụ yinye imidazole otu na diazobenzenesulfonic acid nwere ike ime ihe na-acha aja aja-acha ọbara ọbara ogige, ya bụ, Pauly (Pauly) mmeghachi omume.

109425-51-6 Fmoc-L-His (Trt) -OH nwekwara ike ịbụ otu n'ime Triptorelin Acetate Intermediates.Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly -NH2), bụ gonadotropin na-ahapụ hormone agonist (GnRH agonist) eji dị ka acetate ma ọ bụ pamoate salts.Site na ịkpali mkpali nke pituitary mgbe niile, ọ na-ebelata secretion pituitary nke gonadotropins luteinizing hormone (LH) na follicle stimulating hormone (FSH).Dị ka ndị ọzọ GnRH agonists, triptorelin nwere ike iji na ọgwụgwọ nke hormone na-anabata ọrịa cancer dị ka prostate cancer ma ọ bụ ara ara, precocious puberty, estrogen-adabere ọnọdụ (dị ka endometriosis ma ọ bụ uterine fibroids), na enyemaka mmeputakwa.A na-ejikwa ya dị ka ọgwụgwọ n'ọnọdụ dysphoria okike.

N'oge ọgwụgwọ ọrịa kansa prostate ọ na-ebute mmụba nke testosterone (ihe mbụ elu nke ọkwa testosterone), nke a maara dị ka mmetụta ọkụ.N'ime ụmụ nwoke, mbelata nke ọkwa testosterone dị n'ụdị a na-ahụkarị mgbe nkedo ịwa ahụ na-apụta ihe dịka izu abụọ ma ọ bụ anọ ka mmalite ọgwụgwọ.N'ụzọ dị iche, gonadotropin-na-ahapụ hormone antagonists adịghị eme ka ịwa ahụ, ma na mberede mbelata nke testosterone etoju.

ngwaahịa ndị metụtara ya

L-Ya-OH D-Ya-OH L-His(trt)-OH D-His(trt)-OH
Boc-L-His-OH Boc-L-His(trt)-OH Boc-D-His(trt) -OH Fmoc-L-His-OH
Fmoc-D-His (Trt) -OH Boc-His(Trt)-Gly-OH Boc-L-His (Trt) -Aib-OH Fmoc-His (Mmt) -OH

Gịnị mere Họrọ Anyị

1. Banyere MOQ: Anyị nwere ike ịhazigharị ya dịka ihe ị chọrọ.
2. Banyere ihe atụ: Ihe nlele ahụ chọrọ ego nlele, nke nwere ike ibu ibu iji nakọta ma ọ bụ ị nwere ike ịkwụ anyị ụgwọ tupu oge eruo.
3. Ụlọ ihe omumu ihe, enwere ike ịhazi ya dị ka ọnụ ọgụgụ nke ụdị.
4. Anyị na-enye ọrụ kacha mma.Otu ndị ahịa nwere ahụmahụ na-arụ ọrụ maka gị.
5. Banyere mgbanwe: Biko email ma ọ bụ kpaara m nkata na gị mma.


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